Exact variance component tests for longitudinal microbiome studies
نویسندگان
چکیده
منابع مشابه
Variance Component Selection With Applications to Microbiome Taxonomic Data
1 Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, United States, 2 Department of Biostatistics, University of California, Los Angeles, Los Angeles, CA, United States, 3 Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Arizona, Tucson, AZ, United States, 4 Division of Pulmonary, Critical Care, Sleep, and Occ...
متن کاملSemiparametric variance components models for genetic studies with longitudinal phenotypes.
In a family-based genetic study such as the Framingham Heart Study (FHS), longitudinal trait measurements are recorded on subjects collected from families. Observations on subjects from the same family are correlated due to shared genetic composition or environmental factors such as diet. The data have a 3-level structure with measurements nested in subjects and subjects nested in families. We ...
متن کاملExact Tests for Negligible Interaction in Two-way Analysis of Variance/covariance
Statistical analysis of the interaction effect in a two-way analysis of a variance/covariance model (typically unbalanced) is often performed to provide some additional support for the assessment of the main effect of interest. For example, an analysis of treatment-by-center interaction, in addition to the assessment of treatment effect, is required by the International Conference on Harmonizat...
متن کاملVariance component score test for time-course gene set analysis of longitudinal RNA-seq data.
As gene expression measurement technology is shifting from microarrays to sequencing, the statistical tools available for their analysis must be adapted since RNA-seq data are measured as counts. It has been proposed to model RNA-seq counts as continuous variables using nonparametric regression to account for their inherent heteroscedasticity. In this vein, we propose tcgsaseq, a principled, mo...
متن کاملExact Quantification of Variance Error
Abstract: This paper establishes a method for quantifying variance error in cases where the input spectral density has a rational factorisation. Compared to previous work which has involved asymptotic-in-model-order techniques and yielded expressions which are only approximate for finite orders, the quantifications provided here are exact for finite model order, although they still only apply a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetic Epidemiology
سال: 2019
ISSN: 0741-0395,1098-2272
DOI: 10.1002/gepi.22185